| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761634 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠The effect of a newly developed S1P1-selective antagonist on angiogenic responses. ⺠S1P1 is a critical component of VEGF-related angiogenic responses. ⺠S1P1-selective antagonist showed in vitro activity to inhibit angiogenesis. ⺠S1P1-selective antagonist showed in vivo activity to inhibit angiogenesis. ⺠The efficacy of S1P1-selective antagonist for anti-cancer therapies.
Keywords
EGFTNFS1P1PDGFS1PNGFHUVECbFGFFBSBSAECsbovine serum albuminAntagonistAngiogenesissphingosine 1-phosphatefetal bovine serumHuman umbilical vein endothelial cellsEndothelial cellsepidermal growth factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factornerve growth factorbasic fibroblast growth factortumor necrosis factorAntibody
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Authors
Yasuyuki Fujii, Yasuji Ueda, Hidenori Ohtake, Naoya Ono, Tetsuo Takayama, Kiyoshi Nakazawa, Yasuyuki Igarashi, Ryo Goitsuka,