Article ID Journal Published Year Pages File Type
10761638 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► XPD up-regulated the expressions of P53, phospho-P53(ser-15), P21. ► XPD down-regulated the expressions of Bcl-2 and HBx. ► XPD inhibited the viability of HepG2.2.15 and exacerbated the apoptosis. ► Pifithrin-α, Inhibitor of P53, abolished above-mentioned effects of XPD.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
XPD could suppress growth of HepG2.2.15 and down-regulate the expression of hepatitis B virus x protein through P53 pathway
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