Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761740 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠We examined the functional roles of ETS1 in paclitaxel resistance and invasion. ⺠Expression of ETS1 was higher in paclitaxel-resistant PC3 cells than in PC3 cells. ⺠Silencing of ETS1 decreased MDR1 expression and suppressed paclitaxel resistance. ⺠ETS1 knockdown reduced expression and secretion of MMP9 and inhibited invasion.
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Authors
Taku Kato, Yasunori Fujita, Keita Nakane, Toshio Kojima, Yoshinori Nozawa, Takashi Deguchi, Masafumi Ito,