| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761774 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠We construct a cell permeable Tat-ANX1 fusion protein. ⺠We examined the protective effects of Tat-ANX1 protein on OVA-induced asthma in animal models. ⺠Transduced Tat-ANX1 protein protects from the OVA-induced production of cytokines and eosinophils in BAL fluid. ⺠Tat-ANX1 protein markedly reduced OVA-induced MAPK in lung tissues. ⺠Tat-ANX1 protein could be useful as a therapeutic agent for lung disorders including asthma.
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Authors
Sun Hwa Lee, Dae Won Kim, Hye Ri Kim, Su Jung Woo, So Mi Kim, Hyo Sang Jo, Seong Gyu Jeon, Sung-Woo Cho, Jong Hoon Park, Moo Ho Won, Jinseu Park, Won Sik Eum, Soo Young Choi,