Article ID Journal Published Year Pages File Type
10761780 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► Known- dapsone and amiodarone enhance liver microsomal heme-enzyme activity. ► Effect of these molecules on various functionally unrelated heme-enzymes was studied. ► μM-pM concentrations of the additives significantly enhanced catalytic outcomes. ► Allosteric influences are discounted; a new mechanism is proposed. ► pM levels of additives enhancing enzyme activity demonstrated.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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