Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761785 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Lmo2 expression is elevated in Lck-transformed cells. ⺠Both endogenous and exogenous Lck localize in the nucleus. ⺠Nuclear Lck is active in Lck-transformed cells. ⺠Lck binds to the promoter region of Lmo2 gene in vivo. ⺠In contrast to JAK2, Lck does not increase histone H3 phosphorylation on Tyr 41.
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Authors
Srividya Venkitachalam, Fu-Yu Chueh, Chao-Lan Yu,