Article ID Journal Published Year Pages File Type
10761785 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► Lmo2 expression is elevated in Lck-transformed cells. ► Both endogenous and exogenous Lck localize in the nucleus. ► Nuclear Lck is active in Lck-transformed cells. ► Lck binds to the promoter region of Lmo2 gene in vivo. ► In contrast to JAK2, Lck does not increase histone H3 phosphorylation on Tyr 41.
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