Article ID Journal Published Year Pages File Type
10761817 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► We examined molecular basis of chemokine BRAK expression in epithelial cell. ► BRAK was upregulated according to epithelial cell differentiation. ► Calcium/calmodulin signaling affected BRAK expression. ► A transcription factor SP1 binds to the BRAK promoter region. ► BRAK expression was upregulated by SP1 binding to its promoter.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Calcium-calmodulin signaling induced by epithelial cell differentiation upregulates BRAK/CXCL14 expression via the binding of SP1 to the BRAK promoter region
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