Article ID Journal Published Year Pages File Type
10761821 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► PLB phosphorylation in HEK cells increased FRET between YFP-PLB and CFP-SERCA. ► Competition: Expressing loss-of-function PLB mutants in the system decreased FRET. ► The FRET assay could screen potential therapeutic PLB mutants to activate SERCA.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Phospholamban mutants compete with wild type for SERCA binding in living cells
Authors
, , ,