| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761848 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠We use comparative proteomic strategy to identify 16 lupus-related proteins. ⺠Annexin A5 is overexpressed in peripheral blood mononuclear cells of SLE. ⺠Sera Annexin A5 levels of SLE are generally lower than healthy controls. ⺠High sera Annexin A5 levels correlated with lupus-related thrombophilia. ⺠Annexin A5 is partly not associated with its antibodies in the course of SLE.
Keywords
PBMCsmAbpower of hydrogenANXA5annexin A5FIBINRpSTSCTXAPTTPPPIEFAPsIPGimmobilized pH gradientSDS–PAGEMonoclonal antibodyimmunoglobulin ELISAEnzyme-linked immunosorbent assayisoelectric focusingactivated partial thromboplastin timeprothrombin timeperipheral blood mononuclear cellsAntiphospholipid syndromeCyclophosphamidemass spectrometerFibrinogenInternational Normalized RatioMolecular weightplatelet-poor plasma
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Authors
Di Zhou, Na Luo, Qiao Wu, Yi You, Zhifang Zhai, Zhirong Mou, Yuzhang Wu, Fei Hao,