| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761855 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠DNA methylation is associated with gene regulation. ⺠The differentially methylated regions (DMRs) were identified within 1000 bp upstream of intergenic miRNA. ⺠C[N]6CT pattern is frequently occurred in DMRs. ⺠The C[N]6CT sequence pattern in DMRs is a methylation-dependent regulatory motif for intergenic miRNA expression. ⺠C[N]6CT motifs in DMRs are likely to be an important site for intergenic miRNA regulation or recognition.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Kwang Hee Lee, Hyunyoung Kim, Byeong Jae Lee, Kiejung Park,