Article ID Journal Published Year Pages File Type
10761870 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Flt1+/−; Flk1+/− mice show the buphthalmia without hallmarks of glaucoma. ► Intraocular pressure is elevated in Flt1+/−, Flk1+/−, and Flt1+/−; Flk1+/− mice. ► Outflow pathway of the aqueous humor is affected in Flt1+/− and Flk1+/− mice.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice
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