Article ID Journal Published Year Pages File Type
10761885 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► Hyperglycemia increased FFA levels of INS-1 cell via induced CD36. ► CD36 exacerbate glucotoxicity of INS-1 cell. ► Suppression of CD36 reverse insulin secretion of beta-cell. ► Inhibition of CD36 has a protective role in beta-cell injury from glucotoxicity.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Inhibition of fatty acid translocase cluster determinant 36 (CD36), stimulated by hyperglycemia, prevents glucotoxicity in INS-1 cells
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