Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761903 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Coexpression of β-catenin increased voltage-gated kV current in Kv1.5 expressing oocytes. ⺠The effect was not dependent on the stimulation of transcription. ⺠β-catenin enhances the membrane abundance of Kv1.5. ⺠β-catenin fosters insertion of Kv1.5 protein into the plasma membrane. ⺠The effect on Kv1.5 requires the same protein domains that are required for association of β-catenin with cadherin.
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Authors
Carlos Munoz, Roberta H. Tóvolli, Mentor Sopjani, Ioana Alesutan, Rebecca S. Lam, Guiscard Seebohm, Michael Föller, Florian Lang,