Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761959 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Pomegranate fruit extract (PFE) suppressed the elevated serum resistin in mice. ⺠PFE reduced resistin secretion without affecting the mRNA expression in 3T3-L1 cells. ⺠It was suggested that intracellular resistin protein was degraded by PFE treatment. ⺠Ellagic acid was identified as an active component of PFE. ⺠Our study provides a novel mechanism for suppressing resistin secretion.
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Authors
Yasuko Makino-Wakagi, Yukihiro Yoshimura, Yuki Uzawa, Nobuhiro Zaima, Tatsuya Moriyama, Yukio Kawamura,