| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10761968 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Diospyrin diethylether (D7) caused oxidative stress-dependent activation of PC-PLC. ⺠Activated PC-PLC induced a sustained-release of Ca2+ from endoplasmic reticulum. ⺠The elevated cytosolic Ca+2 led to the calpain-caspase12 dependent apoptosis. ⺠D7-Induced Ca+2 also found to accentuate the mitochondrial pathway of apoptosis.
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Authors
Binod Kumar, Amit Kumar, Subhalakshmi Ghosh, Badri N. Pandey, Kaushala P. Mishra, Banasri Hazra,