Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10761985 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Escherichia coli cells require modifying to make ideal hosts for producing glycoproteins. ⺠Codon optimising pglB leads to increased glycosylation efficiency. ⺠Lipid linked precursors do not appear to be limiting for E. coli N-glycosylation. ⺠Increasing expression of WecA improves E. coli N-glycosylation efficiency.
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Authors
Jagroop Pandhal, Pratik Desai, Caroline Walpole, Leyla Doroudi, Dmitry Malyshev, Phillip C. Wright,