| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762011 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Active PAK1(T423E) but not inactive PAK1(K299R) interacted with and phosphorylated β-catenin. ⺠PAK1 phosphorylated β-catenin at serine 663 (S663) in addition to S675. ⺠S663 phosphorylation is observed in colon cancer cell lines which show a higher PAK1 activity. ⺠S663 phosphorylation was important in regulation of the transcriptional activity of β-catenin.
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Authors
Mee-Hee Park, Duk-Joong Kim, Soon-Tae You, Chan-Soo Lee, Hyong Kyu Kim, Seon Mee Park, Eun-Young Shin, Eung-Gook Kim,