| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762019 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Rapamycin (RPM) enhances the susceptibility of PC3 cells to docetaxel. ⺠Low-dosage of docetaxel (DTX) did not reduce survivin expression levels in PC3 cells. ⺠Combination treatment of RPM with DTX suppressed the expression of surviving. ⺠SiRNA against survivin enhanced the susceptibility of PC3 cells to DTX. ⺠RPM and DTX cotreatment inhibited PC3 cell growth and decreased surviving in vivo.
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Authors
Yasuyuki Morikawa, Hidekazu Koike, Yoshitaka Sekine, Hiroshi Matsui, Yasuhiro Shibata, Kazuto Ito, Kazuhiro Suzuki,