| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762023 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠The Acrodysplasia (Adp) mutation arose from the transgene insertion. ⺠Precise imprinting mechanisms and transgene integration sites are not proven in Adp. ⺠The transgene was inserted into the intronic sequences of the Mdga2 gene. ⺠The transgene shows methylation in an imprinted manner in Adp. ⺠Methylation of the transgene seems to relate to the phenotypic expression of Adp.
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Biochemistry
Authors
Mai Suzuki, Davor Solter, Toshio Watanabe,