Article ID Journal Published Year Pages File Type
10762025 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► We determine mechanisms underlying aldosterone-induced apoptosis. ► Aldosterone promotes intracellular ROS production. ► Aldosterone induces endoplasmic reticulum stress. ► Aldosterone induces apoptosis via ROS-mediated, CHOP-dependent activation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Reactive oxygen species-mediated endoplasmic reticulum stress contributes to aldosterone-induced apoptosis in tubular epithelial cells
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