Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762026 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠We examine how radiation affects the expression level and signal pathway of collagen. ⺠TGF-β1 mRNA is elevated earlier than those of collagen genes after irradiation. ⺠Smad pathway mediates the expression of collagen in radiation induced fibrosis. ⺠MAPK pathways are not affected in the expression of collagen after irradiation.
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Authors
Hiroyuki Yano, Ryoji Hamanaka, Miki Nakamura, Hideaki Sumiyoshi, Noritaka Matsuo, Hidekatsu Yoshioka,