| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762047 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Two budding yeast α-tubulin mutants show low levels of α-tubulin at 14 °C. ⺠Higher dosage of a transcriptional repressor Sum1p elevates their α-tubulin levels. ⺠Higher dosage of Sum1 stabilizes microtubules formed by improperly folded tubulin. ⺠Sum1's stabilizing effect extends to wild-type spindle microtubules as well. ⺠Sum1p is a dosage suppressor of microtubule instability against adverse conditions.
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Authors
Subhash Haldar, Sourav Sarkar, Vinay Singh, Pratima Sinha,