| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762066 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠KURMA is a powerful tool for the gene modification in rats. ⺠LDLR mutant rats spontaneously develop dyslipidemia. ⺠LDLR mutant rats show atherosclerosis and xanthoma. ⺠These symptoms are similar to those of human familial hypercholesterolemia.
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Authors
Makoto Asahina, Tomoji Mashimo, Michiyasu Takeyama, Ryuichi Tozawa, Tadatoshi Hashimoto, Akiko Takizawa, Masatsugu Ueda, Toshihiro Aoto, Takashi Kuramoto, Tadao Serikawa,