| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762076 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠AMPK was inactivated together with higher AII level in the kidney of obese mice. ⺠AII-inhibition improved obesity-related AMPK inactivation and hypertension. ⺠AII infusion inactivated AMPK in the kidney and caused salt-sensitive hypertension. ⺠AMPK activation increased sodium excretion and improved salt-sensitive hypertension.
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Authors
Naoko Deji, Shinji Kume, Shin-ichi Araki, Keiji Isshiki, Hisazumi Araki, Masami Chin-Kanasaki, Yuki Tanaka, Akira Nishiyama, Daisuke Koya, Masakazu Haneda, Atsunori Kashiwagi, Hiroshi Maegawa, Takashi Uzu,