Article ID Journal Published Year Pages File Type
10762082 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► RA causes early expression of germ cell-specific genes, Stra8, Dazl and Mvh in ESCs. ► BMP-Smad1/5 pathway is activated by RA treatment. ► Smad1/5 activation is required for RA-stimulated germ cell differentiation.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway
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