| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762106 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Measurement of CCL3 induced calcium release and cell migration. ⺠PLC activation is essential for release of calcium and chemotaxis. ⺠PKC activation is not needed for cell migration. ⺠PKC inhibitors can deplete calcium stores independently of receptor activation. ⺠PKC inhibitors should be used with caution in signalling assays.
Keywords
PBSDMEMG-protein coupled receptor kinaseS.E.MGRKFCSGPCRPLCThapsigarginPKCG protein coupled receptorEDTAEthylenediaminetetraacetic acidChoChinese Hamster Ovarystandard error of meansfoetal calf serumPhosphate buffered salinephospholipase CDulbecco’s modified eagle’s mediumMigrationProtein kinaseProtein kinase CCalciumchemokine receptor
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Authors
C. Moyano Cardaba, R.O. Jacques, J.E. Barrett, K.M. Hassell, A. Kavanagh, F.C. Remington, T. Tse, A. Mueller,