Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762107 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Carnosic acid inhibited LPS-induced inflammation of microglial MG6 cells. ⺠CA induced phase 2 enzymes both in the absence and presence of LPS. ⺠Phase 2 induction by CA may mediate the anti-inflammation in these cells.
Keywords
DMEMPEDLPSNQO1iNOSRT-PCRGCLCHO-1Hemeoxygenase-1Nrf2TBHQGCLMWSTNADPH quinone oxidoreductase 1xCTFBSPhase 2 enzymeDMSOcarnosic acidinterleukintert-butyl hydroquinoneDimethyl sulfoxidefetal bovine seruminducible nitric oxide synthaseantioxidant-response elementNF-E2-related factor-2lipopolysaccharideglutamate-cysteine ligase, catalytic subunitDulbecco’s modified eagle’s mediumMicrogliaNitric oxideAREreverse transcription polymerase chain reactionpat
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Authors
Mika Yanagitai, Sayaka Itoh, Tomomi Kitagawa, Takato Takenouchi, Hiroshi Kitani, Takumi Satoh,