| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762108 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠PrPC in solution acts as a radical scavenger. ⺠PrPC reduces hydrogen peroxide toxicity in astrocytes. ⺠Increase in ROS disrupted the cell cycle in the PrPC-knockout astrocytes. ⺠PrPC prevents the cell death independently of an SOD-like activity.
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Authors
Fernanda R. Bertuchi, Dominique M.G. Bourgeon, Michele C. Landemberger, Vilma R. Martins, Giselle Cerchiaro,