| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762109 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠First study of retinal pigmented epithelial (RPE) cells response to K. pneumoniae. ⺠Stimulation of RPE with live K. pneumoniae induced a 31.5-fold increase in IL-6. ⺠Stimulation of RPE cells with K. pneumoniae induced a 6.5-fold increase in MCP-1. ⺠LPS alone induces the release of IL-6 and MCP-1 in a dose-dependent manner. ⺠K. pneumoniae and its LPS exert a strong pro-inflammatory effect in RPE cells.
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Authors
Andreas Pollreisz, Brian Rafferty, Emil Kozarov, Evanthia Lalla,