Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762111 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠FBXO2 is a lectin-like ubiquitin ligase. ⺠FBXO2 binds only the exposed glycan core of glycoproteins. ⺠This core is only exposed on misfolded or denatured glycoproteins. ⺠Hence, FBXO2 can be used to develop an unfolded glycoprotein assay.
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Authors
Adam Mallinger, Hsiang M. Wen, Geoffrey M. Dankle, Kevin A. Glenn,