Article ID Journal Published Year Pages File Type
10762112 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► l-NMA not only inhibited iNOS dimerization, but also destabilized its dimeric in immune-activated macrophages. ► This inhibitory effect was correlated with NO production, and these effects were reversed by l-arginine. ► Our results suggest that l-NMA can inhibit NO production via inhibition of iNOS dimerization.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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