Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762173 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Glucocorticoids induced adipocytokine dysregulation and ROS in adipocytes. ⺠Such changes were rectified by MR blockade, not by GR antagonist. ⺠In human, adipose MR was increased in parallel with body mass index. ⺠Glucocorticoid-MR pathway may contribute to the obesity-related disorders.
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Authors
Ayumu Hirata, Norikazu Maeda, Hideaki Nakatsuji, Aki Hiuge-Shimizu, Takuya Okada, Tohru Funahashi, Iichiro Shimomura,