Article ID Journal Published Year Pages File Type
10762180 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► BM- and Ad-MSCs produce high amounts of PGE2 in the presence of activated T-cells. ► The elicitation of the PGE2 secretion of MSCs is contact-dependent. ► TNF-α and IFN-γ act synergistically to induce PGE2 production. ► L-NMA could only partially inhibit PGE2 secretion in response to TNF-α and IFN-γ. ► The PGE2 secretion of MSCs is not mediated by a unique molecular mechanism.
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