| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762224 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Ang2 acts as a Tie2 agonist during lymphangiogenesis. ⺠Lymphatic endothelial cells express expression low levels of the Tie1 receptor. ⺠Association of Tie2 with Tie1 negatively regulates the Tie2-agonistic role of Ang2. ⺠Tie1 expression level defines whether Ang2 functions as a Tie2 agonist or antagonist. ⺠These findings contribute to understanding of the context-dependent Ang2.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Sun-Hwa Song, Koung Li Kim, Kyung-Ah Lee, Wonhee Suh,