Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762268 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Rab27b negatively regulates c-kit expression in megakaryocytic lineage cells. ⺠c-kit is degraded by SCF-induced endolysosomal pathway. ⺠Rab27b regulates autocrine secretion of SCF and leads to c-kit degradation.
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Authors
Chisato Tanaka, Hiroaki Kaji, Jinsong He, Ryoichi Hazama, Kunio Yokoyama, Emi Kinoshita, Takayuki Tsujioka, Kaoru Tohyama, Hirohei Yamamura, Hisahide Nishio, Yumi Tohyama,