Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762281 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠KLF10â/â mice exhibited accelerated papilloma development after DMBA/TPA treatment. ⺠KLF10â/â keratinocytes showed increased proliferation and apoptosis. ⺠KLF10â/â MEFs yielded more colonies than wild-type one with H-Ras transfection. ⺠KLF10 dose-dependently activated p21WAF1/CIP1 transcription. ⺠KLF10 is a tumor suppressor and that it targets p21WAF1/CIP1 transcription.
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Authors
Ki-Duk Song, Duk-Jung Kim, Jong Eun Lee, Cheol-Heui Yun, Woon Kyu Lee,