| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762283 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠Vitreous induces morphological changes and cytoskeletal rearrangements in RPE cells. ⺠Rac1 is activated in vitreous-transformed RPE cells. ⺠Rac inhibition prevents morphological changes in vitreous-transformed RPE cells. ⺠Rac inhibition suppresses cytoskeletal rearrangements in vitreous-transformed RPE cells. ⺠The vitreous-induced effects are mediated by a Rac1 GTPase/LIMK1/cofilin pathway.
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Authors
Xionggao Huang, Yantao Wei, Haizhi Ma, Shaochong Zhang,