| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762325 | Biochemical and Biophysical Research Communications | 2011 | 4 Pages |
Abstract
⺠The mammalian embryo is resistant to pro-apoptotic signals early in development. ⺠Early in development, mitochondria are resistant to depolarization. ⺠Also, epigenetic modifications make the DNA inaccessible to DNases. ⺠Subsequently, changes in BCL2 family proteins allow mitochondrial depolarization. ⺠In addition, loss of epigenetic modifications makes the DNA susceptible to DNases.
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Authors
Peter J. Hansen, Justin M. Fear,