| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762368 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Metabolism by intestinal microflora in arbutin-induced toxicity was investigated. ⺠Intestinal microflora is capable of metabolizing arbutin to hydroquinone (HQ). ⺠HQ could decrease cell viability, produce ROS, and induce apoptosis. ⺠Intestinal microflora may be critical for activation of toxic metabolites.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Tilak Khanal, Hyung Gyun Kim, Yong Pil Hwang, Min Jeong Kong, Mi Jeong Kang, Hee Kyung Yeo, Dong Hyun Kim, Tae Cheon Jeong, Hye Gwang Jeong,