Article ID Journal Published Year Pages File Type
10762452 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Expression of Id3 but not Id1 is induced by Wnt3a stimulation in C2C12 cells. ► Wnt3a induces Id3 expression via canonical Wnt/β-catenin pathway. ► Wnt3a-induced Id3 expression does not depend on BMP signaling activation. ► Induction of Id3 expression is critical determinant in Wnt3a-induced cell proliferation and differentiation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression
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