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Pkh1 interacts with and phosphorylates components of the yeast Gcn2/eIF2α system

Article ID Journal Published Year Pages File Type
10762459 Biochemical and Biophysical Research Communications 2012 6 Pages PDF
Abstract
► Pkh1 interacts with all three eIF2 subunits and Gcn2 in vitro. ► Pkh1 co-immunoprecipitates Gcn2. ► Pkh1 can phosphorylate Gcn2 in vitro. ► Pkh1 inactivation does not affect eIF2α-S51 phosphorylation or GCN4 translation.
Keywords
pKaPKBPIFPDK1GCN2Sch9PDK1-interacting fragmentYeastHydrophobic motif
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Pkh1 interacts with and phosphorylates components of the yeast Gcn2/eIF2α system
Authors
M. Kimpe, K. Voordeckers, J.M. Thevelein, G. Van Zeebroeck,
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Journal
Biochemical and Biophysical Research Communications
Journal: Biochemical and Biophysical Research Communications
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