| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762461 | Biochemical and Biophysical Research Communications | 2012 | 4 Pages |
Abstract
⺠The first demonstration that the effect of HIV infection on HDL can be reproduced in a humanized mouse model of HIV infection. ⺠Demonstration of anti-HIV activity of LXR agonist in an NSG mouse model of HIV infection. ⺠Demonstration of protective effect of LXR agonist against HIV-induced reduction of HDL levels in blood. ⺠Supportive evidence for the indirect mechanism of HIV-induced HDL impairment through the release of a soluble factor.
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Authors
Larisa Dubrovsky, Rachel Van Duyne, Svetlana Senina, Irene Guendel, Tatiana Pushkarsky, Dmitri Sviridov, Fatah Kashanchi, Michael Bukrinsky,