Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762496 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Aβ oligomers are neurotoxins and likely the causing agents for Alzheimer's disease. ⺠Aβ42 fusion protein form globular oligomers. ⺠Aβ42 fusion protein oligomers contain SDS-resistant tetramers and hexamers. ⺠Cysteine substitutions at residues 31, 32, 34, 39-41 disrupt Aβ42 oligomerization.
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Authors
Sam Ngo, Zhefeng Guo,