Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10762526 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠We created Mov cell lines whose Chst8 gene is silenced or overexpressed. ⺠No changes of the total sulfated glycosaminoglycans amount are measured. ⺠The chondroitin sulfate amounts are increased in silenced clones. ⺠The amounts of 4-sulfated chondroitin are increased in silenced clones. ⺠The Chst8 silencing decreases the ability for conversion into PrPSc.
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Authors
Renaud Martin, Sandrine Chantepie, Jérôme Chapuis, Aurélien Le-Duc, Abderrahman Maftah, Dulcé Papy-Garcia, Hubert Laude, Jean-Michel Petit, Paul-François Gallet,