| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762527 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠An invertebrate neuropeptide with hydroxyproline, [Hyp6] AKH = Nezvi-AKH, is established. ⺠This octapeptide is found in corpora cardiaca of the green stink bug, Nezara viridula. ⺠Physiologically, Nezvi-AKH mobilizes lipids from the fat body in the bug. ⺠Proline hydroxylation in the peptide precursor occurs naturally in the corpora cardiaca. ⺠The data support an extended peptide family that includes AKH and vertebrate GnRH.
Keywords
Proline hydroxylaseCIDESI-MSRP-HPLCNezara viridulaRPCHGnRHLHRHHYPnuclear magnetic resonanceLC–MSAKHCollision-induced dissociationNMRInsectsStink bugLiquid chromatography-mass spectrometryElectrospray ionization-mass spectrometryMass spectrometryAdipokinetic hormoneluteinizing hormone-releasing hormoneGonadotropin-releasing hormoneluteinizing hormonehydroxyprolinereversed-phase high pressure liquid chromatography
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Biochemistry
![An invertebrate [hydroxyproline]-modified neuropeptide: Further evidence for a close evolutionary relationship between insect adipokinetic hormone and mammalian gonadotropin hormone family](/preview/png/10762527.png "First Page Preview: An invertebrate [hydroxyproline]-modified neuropeptide: Further evidence for a close evolutionary relationship between insect adipokinetic hormone and mammalian gonadotropin hormone family")
Authors
Gerd Gäde, Petr Å imek, Heather G. Marco,