Role of activating transcription factor 3 in low glucose- and thapsigargin-induced apoptosis in cultured mouse islets

Article ID	Journal	Published Year	Pages	File Type
10762578	Biochemical and Biophysical Research Communications	2011	6 Pages	PDF

Abstract

âº Atf3 partly contributes to ER stress-induced apoptosis in mouse islet cells. âº Atf3 partly contributes to low glucose-induced apoptosis in mouse islet cells. âº Atf3 deletion does not alter mouse islet glucose responsiveness.

Keywords

Pancreatic β-cell Endoplasmic reticulum stress Apoptosis activating transcription factor 3 Integrated stress response