| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762601 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Ganodermanontriol (GDNT), a Ganoderma mushroom alcohol, inhibits growth of breast cancer cells. ⺠CDC20 is over-expressed in tumors but not in the tumor surrounding tissue in breast cancer patients. ⺠GDNT inhibits expression of CDC20 in breast cancer cells. ⺠GDNT inhibits cell adhesion, cell migration and cell invasion of breast cancer cells. ⺠GDNT inhibits secretion of uPA and down-regulates expression of uPAR in breast cancer cells.
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Authors
Jiahua Jiang, Andrej Jedinak, Daniel Sliva,