| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762638 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠MEN1 is a autosomal dominantly inherited syndrome characterized by endocrine tumors. ⺠However, the mechanisms underlying the selectivity of tumors remain unclear. ⺠MEN1-related genes, MLL and p27, were predominantly expressed in the endocrine organs. ⺠Tissue-specific haploinsuffiency of MLL may lead to decreases in levels of p27 and p18.
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Authors
Ryo Taguchi, Masanobu Yamada, Kazuhiko Horiguchi, Takuya Tomaru, Atsushi Ozawa, Nobuyuki Shibusawa, Koshi Hashimoto, Shuichi Okada, Tetsurou Satoh, Masatomo Mori,