Article ID Journal Published Year Pages File Type
10762648 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► Irinotecan, but not SN-38, inhibits 5-HT responses of 5-HT3A receptor. ► Irinotecan inhibition is competitive for 5-HT3A and 5-HT3AB receptor. ► Inhibitory effect on 5-HT3A receptor is more potent than that on 5-HT3AB receptor.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Anticancer drug irinotecan inhibits homomeric 5-HT3A and heteromeric 5-HT3AB receptor responses
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