| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10762676 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Effect of ghrelin administration on unloading-induced muscle atrophy was examined. ⺠Ghrelin was administrated to mice undergoing hindlimb suspension. ⺠Ghrelin stimulated GH-STAT5-IGF-1 axis in locally atrophied muscle. ⺠Ghrelin alleviated muscle atrophy and facilitated recovery from muscle atrophy. ⺠Ghrelin administration has therapeutic potential for unloading-induced muscle atrophy.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Keiichi Koshinaka, Koji Toshinai, Arif Mohammad, Kenji Noma, Miki Oshikawa, Hiroaki Ueno, Hideki Yamaguchi, Masamitsu Nakazato,